Cognition

Semax: Research, Benefits & UK Availability

A synthetic peptide derived from ACTH(4-10), researched for nootropic and neuroprotective effects including cognitive enhancement and BDNF upregulation.

Every Peptify Semax batch is independently HPLC-tested by Janoshik Analytical (Czech Republic) and ships with the batch-matched Certificate of Analysis.

What is Semax?

**Cognition research.** Semax is the synthetic ACTH(4-10) derivative with a Pro-Gly-Pro C-terminal extension that resists enzymatic cleavage — a stability modification documented across published neurotrophic literature, with one of the broader receptor-pathway profiles in the cognition research catalogue.

Research has examined BDNF and NGF upregulation, neuroprotection against oxidative stress and ischaemic damage, and modulation of serotonergic, dopaminergic, and cholinergic neurotransmission. Memory, attention, and learning have been investigated as endpoints separate from the underlying neurotrophic mechanism — a research design that separates arousal from cognition as variables.

5mg lyophilised vial sized for dose-response and single-axis cognitive model work. Janoshik-verified, batch-specific COA included. Strictly for in-vitro research.

Key Research Areas

ACTH(4-7) analogue with Pro-Gly-Pro extension — the C-terminal addition resists enzymatic cleavage and substantially extends half-life

BDNF and NGF upregulation documented; neurotrophic factor elevation is the mechanism underlying most published cognitive research

Serotonergic, dopaminergic, and cholinergic pathway modulation characterised — multi-transmitter profile studied across distinct research groups

Neuroprotective properties in ischaemic and oxidative stress models examined alongside the cognitive endpoint work

No stimulant-like side effect profile observed — relevant distinction for research designs that require separation of arousal from cognition

Available from Peptify UK

Semax 5mg£19.99

Semax 10mg

Popular Research Stacks

Cognitive Stack

Combine with Selank for complementary nootropic and anxiolytic research

How to Store Semax

Unreconstituted (Lyophilised Powder)

Store in a cool, dry place away from direct sunlight. For long-term storage, keep refrigerated at 2–8°C. Under these conditions, lyophilised peptides can remain stable for up to 24 months. For extended preservation beyond 24 months, store at -20°C in a freezer.

Reconstituted (Mixed with BAC Water)

Once reconstituted with bacteriostatic water, the peptide solution must be refrigerated at 2–8°C. Use within 4–6 weeks for optimal potency. Do not freeze reconstituted peptides as this may degrade the compound.

General Tips

Always keep vials upright to prevent leakage. Avoid repeated temperature fluctuations — do not leave vials out at room temperature for extended periods. Protect from light exposure by storing in the original packaging or a dark container. Label all vials with the reconstitution date.

Frequently Asked Questions

What is Semax researched for?

Semax is studied for cognitive enhancement, neuroprotection, and attention improvement. It upregulates BDNF and NGF, supporting neuroplasticity.

Is Semax often combined with Selank?

Yes. Semax and Selank target complementary pathways (cognition and anxiety respectively). Peptify offers a pre-blended Selank + Semax 20mg vial.

Buy Semax from Peptify UK

99%+ HPLC-verified purity. Full COA. Same-day UK shipping.

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