Regulation

MOTS-C: Research, Benefits & UK Availability

A mitochondrial-derived peptide researched for metabolic regulation, exercise mimetic effects, and cellular energy homeostasis through AMPK activation.

Every Peptify MOTS-C batch is independently HPLC-tested by Janoshik Analytical (Czech Republic) and ships with the batch-matched Certificate of Analysis.

What is MOTS-C?

**Mitochondrial research.** MOTS-c is one of the few characterised peptides encoded inside the mitochondrial genome — first described in 2015 and now a reference compound in metabolic research, with AMPK pathway activation as the central mechanism studied in the literature.

Research has examined glucose uptake, insulin sensitivity, fatty acid oxidation, and age-related metabolic decline in preclinical models. Nuclear translocation and direct regulation of metabolic gene expression have been investigated as the distinguishing mechanistic features that separate MOTS-c from surface-receptor peptides.

10mg lyophilised vial. 99%+ HPLC-verified purity, batch-specific COA included. For in-vitro research use only.

Key Research Areas

Mitochondria-derived peptide encoded within the mitochondrial genome — not nuclear DNA like most regulatory peptides

AMPK pathway activation characterised as a primary mechanism; described as an exercise-mimetic in published metabolic research

Glucose uptake and insulin sensitivity examined in preclinical metabolic models under high-fat diet conditions

Nuclear translocation documented — acts directly on metabolic gene regulation rather than through surface receptor signalling

Physical performance and endurance capacity in aged models examined alongside metabolic decline endpoints

Available from Peptify UK

Mots C 10mg

MOTS-C 40mg£84.99

Popular Research Stacks

Metabolic Stack

Pair with NAD+ for comprehensive cellular energy research

How to Store MOTS-C

Unreconstituted (Lyophilised Powder)

Store in a cool, dry place away from direct sunlight. For long-term storage, keep refrigerated at 2–8°C. Under these conditions, lyophilised peptides can remain stable for up to 24 months. For extended preservation beyond 24 months, store at -20°C in a freezer.

Reconstituted (Mixed with BAC Water)

Once reconstituted with bacteriostatic water, the peptide solution must be refrigerated at 2–8°C. Use within 4–6 weeks for optimal potency. Do not freeze reconstituted peptides as this may degrade the compound.

General Tips

Always keep vials upright to prevent leakage. Avoid repeated temperature fluctuations — do not leave vials out at room temperature for extended periods. Protect from light exposure by storing in the original packaging or a dark container. Label all vials with the reconstitution date.

Frequently Asked Questions

What is MOTS-C researched for?

MOTS-C is studied as an exercise mimetic that activates AMPK, enhances glucose uptake, and improves metabolic homeostasis.

What sizes does Peptify offer?

Peptify offers MOTS-C in 10mg and 40mg vials, both at 99%+ purity with COA.

Buy MOTS-C from Peptify UK

99%+ HPLC-verified purity. Full COA. Same-day UK shipping.

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