Regulation

NAD+: Research, Benefits & UK Availability

A critical coenzyme involved in over 500 enzymatic reactions, researched for cellular energy production, DNA repair, and longevity pathways.

What is NAD+?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme involved in over 500 enzymatic reactions and has been studied extensively in the context of ageing, cellular energy, and longevity research.

As a cofactor for sirtuins (SIRT1-7) and PARP enzymes, NAD+ has been investigated for its roles in mitochondrial biogenesis, DNA repair, and stress resistance. Research has examined the relationship between age-related NAD+ decline and metabolic dysfunction.

The 500mg formulation is sized for research protocols examining systemic repletion models where lower per-dose quantities would require frequent reconstitution. Supplied for in-vitro research use only; dispatched same-day from the UK with batch-specific COA downloadable from every product page.

Key Research Areas

Cofactor in over 500 enzymatic reactions — participates in both oxidative phosphorylation and non-redox signalling pathways

Sirtuin (SIRT1-7) activation dependent on NAD+ availability; PARP DNA repair enzymes consume it as a substrate

Measurable age-related NAD+ decline in human tissue documented; decline rate and tissue distribution characterised in published data

Mitochondrial biogenesis, genomic stability, and circadian rhythm regulation all studied as NAD+-dependent processes

High-dose 500mg formulation — sized for research protocols examining systemic NAD+ repletion models

Available from Peptify UK

Nad 500mg

Popular Research Stacks

Longevity Stack

Combine with MOTS-C for metabolic and mitochondrial research

Cellular Energy Stack

Add SS-31 for mitochondrial-targeted longevity protocols

How to Store NAD+

Unreconstituted (Lyophilised Powder)

Store in a cool, dry place away from direct sunlight. For long-term storage, keep refrigerated at 2–8°C. Under these conditions, lyophilised peptides can remain stable for up to 24 months. For extended preservation beyond 24 months, store at -20°C in a freezer.

Reconstituted (Mixed with BAC Water)

Once reconstituted with bacteriostatic water, the peptide solution must be refrigerated at 2–8°C. Use within 4–6 weeks for optimal potency. Do not freeze reconstituted peptides as this may degrade the compound.

General Tips

Always keep vials upright to prevent leakage. Avoid repeated temperature fluctuations — do not leave vials out at room temperature for extended periods. Protect from light exposure by storing in the original packaging or a dark container. Label all vials with the reconstitution date.

Frequently Asked Questions

Why is NAD+ important in research?

NAD+ is essential for sirtuin activation, mitochondrial function, and DNA repair. Levels decline with age, making it a key focus of longevity research.

What is the purity of Peptify NAD+?

Peptify NAD+ is 99%+ HPLC-verified with a full Certificate of Analysis provided with every batch.

How should NAD+ be stored?

Store lyophilised NAD+ at -20C for long-term stability. Reconstituted NAD+ should be kept at 2-8C.

Buy NAD+ from Peptify UK

99%+ HPLC-verified purity. Full COA. Same-day UK shipping.

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